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Updated: Aug 19, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
Retrospective analysis of predictive factors for recurrence after curatively resected papillary thyroid carcinoma
Katsuhiro Tanaka1, Hiroshi Sonoo, Mai Hirono
1Department of Breast and Thyroid Surgery, Kawasaki Medical School, 577 Matsushima, Kurashiki, 701-0192, Japan.
Purpose:
This retrospective study analyzes the predictive factors after curative surgery for papillary thyroid carcinoma (PTC).
Methods:
We analyzed 386 patients who underwent a curative operation for PTC in our hospital between 1977 and 1997, subject to the inclusion criteria.
Results:
According to univariate analysis, pathological lateral cervical lymph node involvement (P < 0.0001), dedifferentiation of the tumor (P < 0.002), male sex (P < 0.0001), a large tumor (P < 0.005), and an age of over 50 years (P < 0.05) were significant factors. Cox's proportional hazard model showed that a man (P < 0.05), aged over 50 years (P < 0.05), who had a large primary tumor (P < 0.05) with dedifferentiation (P < 0.05), and pathological lateral cervical lymph node metastasis (P < 0.005) was more likely to have recurrence of PTC.
Conclusions:
Determining whether lymph node metastasis exists could be useful for predicting recurrence in patients who have undergone curative resection of PTC.
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