Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Bronchial hyperresponsiveness in irritable bowel syndrome.

Dae Won Jun¹, Oh Young Lee, Ho Joo Yoon

¹Divisions of Gastroenterology, Hanyang University School of Medicine, Seoul, South Korea.

Digestive Diseases and Sciences

|September 1, 2005

Summary

This study found no direct link between irritable bowel syndrome (IBS) and bronchial hyperresponsiveness in most patients. Further research may explore potential connections in specific IBS subgroups.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Higher Incidence of Hepatocellular Carcinoma in Suppressed Hepatitis B Cirrhosis Compared With Cured Hepatitis C Cirrhosis.

The American journal of gastroenterology·2026

Same author

Rule-Out Cutoff of Two-Dimensional Shear Wave Elastography for Significant Fibrosis in Metabolic Dysfunction-Associated Steatotic Liver Disease: Systematic Review, Meta-Analysis, and External Validation.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2026

Same author

Polygenic Risk Score Predicts Prognosis in Nonobese Metabolic Dysfunction-Associated Steatotic Liver Disease but not in Obese Metabolic Dysfunction-Associated Steatotic Liver Disease in Japan: A Multicenter Cohort Study.

Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association·2026

Same author

The MASLD Journey in the General Population: Linkage-to-Care and Patient-Reported Uptake of Fibrosis Risk Assessment.

Liver international : official journal of the International Association for the Study of the Liver·2026

Same author

Correction to: Misclassification of Alcohol Use Disorder in MASLD and MetALD: Prevalence, Clinical Characteristics, and Outcomes.

Gut and liver·2026

Same author

Long-Term Mortality Following Hepatitis C Cure in a Real-World Multinational Cohort.

Liver international : official journal of the International Association for the Study of the Liver·2026

Area of Science:

Pulmonology
Gastroenterology
Clinical Medicine

Background:

Irritable bowel syndrome (IBS) frequently presents with extraintestinal symptoms.
Emerging evidence suggests a potential association between IBS and bronchial hyperresponsiveness, though this link remains debated.

Purpose of the Study:

To investigate the potential relationship between irritable bowel syndrome (IBS) and bronchial hyperresponsiveness.

Main Methods:

Pulmonary function tests, methacholine challenge tests, and skin prick tests were administered to 42 IBS patients and 42 controls.
Analysis included standard pulmonary function parameters (FEV(1)%, FCV%, FVC/FEV(1), FEF(25-75)%) and methacholine provocation test results (PC(20)).

Main Results:

Related Experiment Videos

No statistically significant differences were observed in pulmonary function test parameters between IBS patients and controls.

A small number of participants in both groups tested positive for bronchial hyperresponsiveness, but all methacholine challenge test PC(20) values were above 16 mg/ml, indicating no significant hyperresponsiveness.

Conclusions:

The study did not establish a clear relationship between bronchial hyperresponsiveness and irritable bowel syndrome in the studied cohort.
A possible association may exist within specific subpopulations of IBS patients, warranting further investigation.