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Updated: Aug 16, 2026

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
Published on: August 15, 2016
[Randomized controlled study of S (+) -ismer of ibuprofen supporsitory]
Yun-Hui You1, Cai-Ling Wu, Jie-Sheng Gao
1Department of Rheumatology, Xiangya Hospital, Central South University Changsha, China.
Objective:
To evaluate the efficacy and safety of S (+) - ismer of ibuprofen supporsitory.
Methods:
One hundred and three cases of postopterative pain and 60 cases of fever, altogether 163 patients were randomly divided into 2 groups: S (+) -ismer of ibuprofen supporsitory treatment group (one supporsitory per day for 3 days) and ibuprofen supporsitory treatment group (one supporsitory per day for 3 days). The therapeutic effect was assessed and the side-effects were observed between the 2 groups.
Results:
After being given medicine in the first 4 hours, pain intensity difference, pain remission degree and the dropped level of fever in S (+) -ismer of ibuprofen were all bigger than those of the ibuprofen supporsitory treatment group. There was no difference in side-effects between the 2 groups.
Conclusion:
Therapeutic effect of S (+) -ismer of ibuprofen supporsitory is definite, whose action appears more quickly and stronger and it has fewer side-effects than those of ibuprofen supporsitory.
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