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Effect of ghrelin on activities of some lysosomal hydrolases in rabbits
Bozena Witek1, Ewa Ochwanowska, Jan Rafay
1Department of Genetics, Institute of Biology, Swietokrzyska Academy, Kielce, Poland. b.witek@pu.kielce.pl
Objectives:
Observing the changes of activity of some lysosomal enzymes in blood serum of female rabbits subjected to injection of 10 microg of ghrelin/kg of body weight.
Methods:
In the blood serum the activity of cathepsins D and L, alanine aminopeptidase, acid phosphatase, lysosomal lipase and lysosomal esterase was determined.
Results:
As a result of ghrelin injection the activity of all the enzymes examined in blood serum increased markedly.
Conclusion:
Changes of lysosomal enzymes activities in the blood serum caused by the effects of ghrelin should be regarded as the response of the lysosomal system.
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