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Updated: Aug 16, 2026

Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus
Published on: December 7, 2013
The evolution of the atheromatous plaque: ultrastructural evidence
A Aleotti1, P Boldrini, M R Bovolenta
1Center of Electron Microscopy, University of Ferrara, Chieti, Italy. arrigo.aleotti@unife.it
Abstract:
Our understanding of endothelial physiology is overdue compared with other areas of study. For too many years the complex mysteries of this thin single-layered cellular lamina covering the whole of the vascular network, from the large conduction vessel to the smallest resistance and diffusion vessel, have been hidden by an organ-based science more focused on organ pathology than on ultrastructural physiopathology. We tried to follow chronologically the alteration stages of this system of membranes in relation to the development of the atherosclerotic plaque in human biopsy.
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