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Primary pulmonary AIDS-related lymphoma
Marcelo Corti1, María F Villafañe, Norberto Trione
1Infectious Diseases, F.J. Muñiz Hospital, Buenos Aires, Argentina. marcelocorti@fibertel.com.ar
Revista Do Instituto De Medicina Tropical De Sao Paulo
|September 3, 2005
Summary
Primary pulmonary lymphoma in patients with acquired immunodeficiency syndrome (AIDS) is rare. This case highlights a unique presentation of total left lung atelectasis in a patient with AIDS-related non-Hodgkin's lymphoma.
Area of Science:
- Oncology
- Infectious Diseases
- Pulmonology
Background:
- Extranodal involvement is frequent in HIV-associated lymphomas.
- Primary pulmonary lymphoma in AIDS patients is exceptionally rare, with limited published cases.
- Patients typically present with advanced immunodeficiency and nonspecific symptoms.
Observation:
- Chest radiography often reveals peripheral nodules or cavitary masses.
- This report details a unique case of primary pulmonary lymphoma presenting as complete left lung atelectasis.
- The patient had advanced immunodeficiency consistent with acquired immunodeficiency syndrome (AIDS).
Findings:
- Primary pulmonary lymphoma in AIDS is typically a high-grade B-cell non-Hodgkin lymphoma.
- Epstein-Barr virus is strongly implicated in the pathogenesis of these lymphomas.
- The presented case exhibited an unusual clinical manifestation of total lung collapse.
Implications:
- This case expands the spectrum of clinical presentations for AIDS-related pulmonary lymphoma.
- Increased awareness of rare presentations is crucial for timely diagnosis and management.
- Understanding the diverse manifestations aids in improving patient outcomes for HIV-infected individuals with lymphoma.