Cytotoxic T-cell non-Hodgkin's lymphoma of the thyroid gland
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Updated: Aug 16, 2026

An Orthotopic Mouse Model of Anaplastic Thyroid Carcinoma
Published on: April 17, 2013
Akio Okamoto1, Kyoko Namura, Hitoji Uchiyama
1Department of Medicine, Nantan General Hospital, Yagi, Japan.
Abstract:
An 86-year-old female was diagnosed with peripheral T-cell lymphoma, unspecified, which affected only her thyroid gland. Lymphoma cells were TIA-1(+), suggesting cytotoxic T-cell origin. She had not suffered from autoimmune thyroiditis and showed normal thyroid function. Without any specific therapies, the lymphomatous lesion showed the partial spontaneous regression before diagnostic hemithyroidectomy, and she had been well for 2 years without relapse. This is the first case of primary thyroid lymphoma of cytotoxic T-cell origin that showed spontaneous regression.
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