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Published on: November 4, 2010
Key issues in inhalation therapy in children
1Princess Amalia Children's Clinic, Isala Klinieken, Zwolle, The Netherlands. p.l.p.brand@isala.nl
Insights
Proper inhaler technique is crucial for pediatric asthma control. Studies show nebulizers and metered dose inhalers have similar efficacy, but correct inhaler use is challenging for children and requires ongoing education.
Area of Science:
- Pediatric Pulmonology
- Respiratory Medicine
- Asthma Management
Background:
- Effective asthma control in children necessitates proper education, correct medication, and appropriate inhaler selection for optimal lung deposition.
- Common misconceptions exist regarding nebulizer vs. pressurized metered dose inhaler (pMDI) plus spacer efficacy, the ease of correct inhaler use, and the persistence of learned techniques.
Purpose of the Study:
- To address misconceptions about pediatric asthma inhaler use and efficacy.
- To highlight the challenges children face with inhaler technique and the need for repeated instruction.
- To define the characteristics of an ideal inhaler for pediatric asthma patients.
Main Methods:
- Review of recent studies comparing nebulizers and pMDI plus spacer for acute and maintenance asthma therapy in children.
- Analysis of factors contributing to incorrect inhaler use and technique deterioration over time.
- Evaluation of the features of the Novolizer dry powder inhaler against ideal characteristics for pediatric use.
Main Results:
- Nebulizers and pMDI plus spacer demonstrate comparable efficacy for asthma treatment in children.
- Children frequently use inhaler devices incorrectly, even after initial instruction.
- Correct inhalation technique declines over time, underscoring the need for continuous education.
Conclusions:
- Repeated education is essential to achieve and maintain correct inhalation technique in children with asthma.
- The ideal inhaler for children should be easy to use, provide consistent dosing, and offer feedback.
- The Novolizer multidose dry powder inhaler exhibits many desirable characteristics for pediatric asthma management.
Abstract:
In order to achieve asthma control it is essential that children receive the appropriate education and training pertaining to the management of their disease, are prescribed the correct medication according to severity, and most importantly, are prescribed the correct inhaler to ensure medication is deposited in their lungs. There are three major misconceptions which physicians and patients have regarding the use of inhalers in children. Firstly, that the nebulizer is more effective than a pressurised metered dose inhaler (pMDI) plus spacer in treating acute asthma in children. Secondly that using an inhaler correctly is easy, and lastly that correct use of the inhaler, once taught, persists over time. However, recent studies have shown that these conceptions are false. Firstly, comparable efficacy is achieved by treatment with inhaled corticosteroids or bronchodilators delivered through a nebulizer and a pMDI plus spacer, both when used to treat acute asthma and for maintenance therapy. Secondly, contrary to general opinion, using an inhaler correctly is difficult for children. Many children with asthma use their inhaler devices incorrectly, even after instruction for correct use of the inhaler. Thirdly, correct inhalation technique deteriorates over time; and inhalation instructions, therefore, should be given repeatedly to achieve and maintain correct inhalation technique in asthmatic children. The profile of the ideal inhaler comprises good drug deposition in the lower airways, deliverance of a consistent dose, being easy to teach and to use correctly, and being small in size and convenient to handle. It should also be multidose, require a low inspiratory airflow for activation, provide feedback to patients on correct use of the inhaler, be re-usable, have an appealing design and feel, and have a reliable dose counter which may help to monitor the patient's compliance. The Novolizer device, a new multidose dry powder inhaler (DPI), shows many of these characteristics making it potentially very suitable for children with asthma.
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