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Female predominance in intermittent exotropia
Kevin J Nusz1, Brian G Mohney, Nancy N Diehl
1Department of Ophthalmology, Mayo Clinic and Mayo Foundation, 200 First Street SW, Rochester, MN 55905, USA.
American Journal of Ophthalmology
|September 6, 2005
Summary
Intermittent exotropia, a common eye condition, occurred nearly twice as often in girls compared to boys. However, no significant differences were found in clinical factors or family history between genders.
Area of Science:
- Ophthalmology
- Pediatric ophthalmology
- Epidemiology
Background:
- Intermittent exotropia is a common form of strabismus in children.
- Understanding epidemiological patterns, including gender distribution, is crucial for diagnosis and management.
Purpose of the Study:
- To investigate potential gender disparities in the incidence and characteristics of intermittent exotropia among children.
- To compare clinical presentation and risk factors between male and female pediatric patients diagnosed with intermittent exotropia.
Main Methods:
- A retrospective, population-based cohort study was conducted.
- Medical records of residents under 19 years old diagnosed with intermittent exotropia between 1975 and 1994 in Olmsted County, Minnesota, were reviewed.
Main Results:
- The study included 184 patients, with girls comprising 64.1%.
- The age-adjusted incidence rate for girls was 38.3 per 100,000, significantly higher than the 20.8 per 100,000 rate for boys (P < .0001).
- No significant differences were observed between genders regarding family history of strabismus, birth weight, prematurity, age at diagnosis/surgery, refractive error, or initial deviation angle.
Conclusions:
- Intermittent exotropia is nearly twice as common in girls compared to boys within this population.
- Despite the higher incidence in girls, no significant gender-based differences were found in historical or clinical factors.