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[Isolated splenic tuberculosis].

T Sato1, M Mori, T Inamatsu

  • 1Department of Medicine, Tokyo Metropolitan Geriatric Hospital.

Nihon Ronen Igakkai Zasshi. Japanese Journal of Geriatrics
|April 1, 1992
PubMed
Summary
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This case report details a rare instance of splenic tuberculosis in a 79-year-old man. Diagnosis involved imaging and surgery, confirming tuberculosis of the spleen (splenic tuberculosis) and leading to successful treatment.

Area of Science:

  • Infectious Diseases
  • Gastroenterology
  • Pathology

Background:

  • Splenic tuberculosis is an exceptionally rare manifestation of Mycobacterium tuberculosis infection.
  • Isolated splenic tuberculosis often presents with non-specific symptoms, complicating diagnosis.

Observation:

  • A 79-year-old male presented with fever and weight loss, exhibiting inguinal lymphadenopathy and a positive tuberculin skin test.
  • Abdominal imaging revealed splenomegaly with multiple low-density lesions and para-aortic lymphadenopathy, despite a clear chest X-ray.
  • Surgical exploration and splenectomy were necessary for definitive diagnosis due to inconclusive initial investigations.

Findings:

  • Histopathological examination of the spleen showed numerous nodules containing acid-fast bacilli.

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  • The resected spleen weighed 700g and displayed extensive nodular changes.
  • Post-splenectomy and antituberculous therapy resulted in fever resolution.
  • Implications:

    • This case underscores the importance of considering splenic tuberculosis in the differential diagnosis of fever of unknown origin with splenomegaly.
    • Early recognition and appropriate treatment are crucial for managing this rare condition.
    • Further research into the diagnostic and therapeutic strategies for splenic tuberculosis is warranted.