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Enhancement of immune responses to an HBV DNA vaccine by electroporation
A Luxembourg1, D Hannaman, B Ellefsen
1Ichor Medical Systems, 6310 Nancy Ridge Drive, Ste 107, San Diego, CA 92121, USA. aluxembourg@ichorms.com
Vaccine
|September 6, 2005
Abstract:
These studies document the ability of electroporation (EP)-based DNA vaccination to induce multi-specific CTL responses to hepatitis B virus (HBV) DNA vaccination in normal mice and marked immune responses to multivalent HBV DNA immunization in larger animal species. These results suggest that electroporation-mediated HBV DNA vaccination is worth pursuing as a treatment for chronic HBV infection.

