Related Experiment Video

Updated: Aug 16, 2026

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis
06:19

A Rat Model of Mild Intrauterine Hypoperfusion with Microcoil Stenosis

Published on: January 7, 2018

Is blood pressure increased 19 years after intrauterine growth restriction and preterm birth? A prospective follow-up

Mandy G Keijzer-Veen1, Martijn J J Finken, Jeroen Nauta

  • 1Department of Pediatric Nephrology, Erasmus MC-Sophia Children's Hospital, University Medical Center Rotterdam, Rotterdam, The Netherlands.

Pediatrics
|September 6, 2005
PubMed

Insights

This study found high blood pressure in young adults born preterm, but intrauterine growth restriction was not a contributing factor. Current weight and BMI were the best predictors of systolic blood pressure.

Area of Science:

  • Neonatal Medicine
  • Cardiovascular Health
  • Pediatric Endocrinology

Background:

  • Preterm birth is associated with long-term health issues.
  • Intrauterine growth restriction (IUGR) may impact later cardiovascular health.
  • Understanding risk factors for hypertension in young adults born preterm is crucial.

Purpose of the Study:

  • To investigate if intrauterine growth restriction (IUGR) predisposes individuals born very preterm to high blood pressure (BP) at age 19.
  • To assess the prevalence of hypertension and prehypertension in young adults born preterm.

Main Methods:

  • Prospective follow-up study of individuals born preterm in the Netherlands.
  • BP measurements (systolic, diastolic, mean) and plasma renin activity obtained at age 19.
  • Comparison between individuals born with gestational age <32 weeks and those born with gestational age >=32 weeks and birth weight <1500 g.

Main Results:

  • Increased prevalence of hypertension and prehypertension observed in the preterm group.
  • IUGR, birth weight, gestational age, and plasma renin activity were not associated with BP at age 19.
  • Current weight and Body Mass Index (BMI) were the strongest predictors of systolic BP.

Conclusions:

  • Young adults born preterm exhibit a high prevalence of hypertension compared to the general population.
  • The study does not support the hypothesis that low birth weight (IUGR) is linked to increased BP in very preterm individuals at young adulthood.
Abstract

More Related Videos

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction14:19

Fetal Echocardiography and Pulsed-wave Doppler Ultrasound in a Rabbit Model of Intrauterine Growth Restriction

Published on: June 29, 2013

Related Concept Videos

Factors affecting Blood pressure01:28

Factors affecting Blood pressure

Several physiological and lifestyle factors influence blood pressure (BP). Understanding these factors is crucial as they are significant in patient education and blood pressure management.
Physiological Factors:
Pre-Procedural Guidelines for Assessing Blood Pressure01:10

Pre-Procedural Guidelines for Assessing Blood Pressure

Accurate blood pressure assessment is crucial for diagnosing and managing various health conditions. To ensure the reliability of these measurements, healthcare professionals must adhere to standardized pre-procedural guidelines. These guidelines enhance patient safety and improve the overall quality of healthcare. The following steps are essential for obtaining accurate and consistent blood pressure readings, from using the appropriate tools to ensuring effective communication with the patient.
Measurement of Blood Pressure01:17

Measurement of Blood Pressure

Assessing blood pressure is a standard procedure executed in virtually all medical environments. The method utilized today was established over a hundred years ago by an innovative Russian doctor, Dr. Nikolai Korotkoff. The soft ticking noise, known as Korotkoff sounds, heard while taking blood pressure readings results from turbulent blood flow within the vessels. The apparatus required for this procedure includes a sphygmomanometer, a blood pressure cuff attached to a gauge, and a stethoscope.
Special considerations while measuring blood pressure01:28

Special considerations while measuring blood pressure

When assessing blood pressure (BP), healthcare professionals must consider various factors and potential unexpected outcomes to ensure accurate readings and provide proper patient care. Adhering to these guidelines is essential to achieving the most reliable results.
Monitoring Both Arms:
Monitoring BP in both arms during the initial assessment is advisable, as the systolic value may differ by five to ten mm Hg between arms. For subsequent BP assessments, use the arm with the higher reading.
Hypertension III: Clinical Manifestations and Diagnostic Studies01:30

Hypertension III: Clinical Manifestations and Diagnostic Studies

Hypertension is asymptomatic and also referred to as the "silent killer" until it progresses to a severe stage or causes target organ disease. Patients may experience symptoms stemming from the strain on blood vessels and tissues in various organs or the heart's increased workload.Physical exams might show no abnormalities other than high blood pressure. Signs of vascular damage, when present, correspond to the organs supplied by the affected vessels, leading to target organ damage. For...
Assessment of blood pressure in brachial artery(two-step method)01:23

Assessment of blood pressure in brachial artery(two-step method)

Measuring blood pressure is a fundamental skill in healthcare that aids in diagnosing and monitoring hypertension and other cardiovascular conditions. An aneroid sphygmomanometer, commonly used in clinical settings, offers a manual and precise method for blood pressure measurement. The technique for using this instrument involves specific steps that must be carefully executed to ensure accuracy. The following detailed description outlines a two-step technique for assessing blood pressure using...