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Published on: January 21, 2018
Nasal wall compliance in vasomotor rhinitis
Jean-François Papon1, Lydia Brugel-Ribere, Redouane Fodil
1Physiopathologie et Thérapeutique Respiratoires INSERM UMR 651, Créteil, France.
Journal of Applied Physiology (Bethesda, Md. : 1985)
|September 6, 2005
Summary
Patients with vasomotor rhinitis show abnormal nasal vascular responses. Nasal compliance measurement may help diagnose this condition, which is currently a diagnosis of exclusion.
Area of Science:
- Otolaryngology
- Rhinology
- Physiology
Background:
- Nasal compliance reflects nasal mucosal blood volume.
- Vasomotor rhinitis involves abnormal nasal vascular responses.
- Current diagnosis of vasomotor rhinitis is by exclusion.
Purpose of the Study:
- To investigate nasal vascular responses in vasomotor rhinitis.
- To compare nasal cross-sectional area and compliance in patients and controls.
- To assess the effect of mucosal decongestion on nasal compliance.
Main Methods:
- Acoustic rhinometry was used to measure nasal area and compliance.
- Measurements were taken at varying pressures before and after decongestion.
- Oxymetazoline was used for mucosal decongestion in 10 patients and 10 controls.
Main Results:
- Nasal cross-sectional areas were similar between groups at atmospheric pressure.
- Mucosal decongestion did not decrease nasal compliance in vasomotor rhinitis patients.
- Healthy subjects showed decreased nasal compliance after decongestion.
Conclusions:
- Results suggest autonomic dysfunction and paradoxical nasal mucosal response in vasomotor rhinitis.
- Nasal compliance measurement may offer a potential diagnostic tool for vasomotor rhinitis.
- Distinctive nasal compliance behavior differentiates patients from healthy individuals.
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