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[Optic neuropathy associated with primary antiphospholipid syndrome]
A Lecleire-Collet1, D Milea, G Brasseur
1Service d'ophtalmologie, Hôpital Charles Nicolle, CHU, Rouen. colletamelie@hotmail.com
Journal Francais D'Ophtalmologie
|September 6, 2005
Summary
Primary antiphospholipid syndrome can cause atypical optic neuropathy, leading to vision loss. Prompt diagnosis and anticoagulation therapy resulted in complete vision recovery and prevented further thrombotic events.
Area of Science:
- Ophthalmology
- Rheumatology
- Neurology
Background:
- Primary antiphospholipid syndrome (APS) is a systemic autoimmune disorder characterized by recurrent thrombotic events or pregnancy complications.
- Optic neuropathy is a potential, though less common, manifestation of APS, often presenting with varied visual disturbances.
Observation:
- A 45-year-old male presented with atypical unilateral optic neuropathy, initially causing significant vision impairment.
- The patient's clinical presentation was ultimately diagnosed as primary antiphospholipid syndrome.
Findings:
- The patient experienced a complete recovery of vision over several months despite the initial severity.
- Long-term oral anticoagulation therapy was initiated following the diagnosis of APS.
Implications:
- This case highlights the importance of considering APS in the differential diagnosis of unexplained optic neuropathies.
- Effective anticoagulation management can prevent further systemic thrombotic complications in APS patients with neurological involvement.
- Early recognition and treatment of APS-related optic neuropathy may lead to favorable visual outcomes.