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Published on: June 18, 2021
[Headache from idiopathic cervical artery dissection: time-course and follow-up]
1Service de Neurologie et Pathologie Neurovasculaire, CHRU de Lille, 59037 Lille Cedex, France. clucas@chru-lille.fr
Insights
Headache often improves after cervical artery dissection (CAD), with most migraine sufferers experiencing fewer attacks. Some patients may develop new headaches post-CAD, warranting further research into these complex relationships.
Area of Science:
- Neurology
- Vascular Neurology
- Headache Medicine
Context:
- Headache is a common symptom during the acute phase of cervical artery dissection (CAD), often mimicking migraine.
- Migraine is recognized as an independent vascular risk factor for stroke.
- Recent studies suggest migraine may also be an independent risk factor for CAD.
Purpose:
- To investigate the course of headache in patients with spontaneous cervical artery dissection (CAD).
- To analyze changes in pre-existing headache patterns and the development of new headaches after CAD.
- To explore the complex relationship between CAD, migraine, and headache disorders.
Summary:
- This study analyzed headache patterns in 42 patients hospitalized for spontaneous CAD.
- Pre-existing headaches, including migraine, improved in 95.5% of patients post-CAD.
- New-onset headaches occurred in 7 patients after CAD, with migraine and tension-type headaches being most common.
Impact:
- Findings indicate that pre-existing headaches, particularly migraine, often improve following spontaneous CAD.
- The study highlights a potential link between CAD and headache disorders, suggesting further investigation into underlying mechanisms.
- Understanding these relationships may inform clinical management and future research into vascular headaches and dissection.
Abstract:
Headache is very common during the acute phase of cervical artery-dissection (CAD) sometimes mimicking a migraine attack. However, the relationships between these two conditions are complex and the course of headache in patients with CAD is not well known. Indeed, migraine is an independent vascular risk factor of stroke, especially ischemic stroke. Recently, a case-control study has shown that migraine is an independent risk factor of CAD. We have studied the course of headache in all consecutive patients hospitalized for spontaneous CAD in our stroke unit between 1998 and 2001, confirmed by a mural hematoma on MRI. We conducted patient interviews with a structured questionnaire about headache (according to the International Headache Society criteria) before and after the CAD. Forty-two patients had had a spontaneous CAD during this period. Twenty-two had had headache in the past: 9 migraine without aura, 5 migraine with aura and 8 with episodic tension-type headache. The headache improved in 22 patients (95.5 percent) after the spontaneous CAD. Of 14 patients who were migrainers, 13 (92 percent) had fewer migraine attacks after the CAD. Only 7 patients, without previous headache developed new headache after CAD: three migraine without aura, three episodic tension-type headache and one chronic tension-type headache. For the majority of patients the pre-existing headache improved after spontaneous CAD. A few patients developed a new headache only after CAD. Relationships between CAD, migraine and elastic tissue disorder should now to be explored.
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