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In vivo Reprogramming of Adult Somatic Cells to Pluripotency by Overexpression of Yamanaka Factors
Published on: December 17, 2013
Diurnal dynamics of cell proliferation in rat liver during early postnatal ontogeny and effect of epidermal growth
S N Smirnov1, V B Zakharov, S G Mamontov
1Lugansk State Medical University; Russian State Medical University, Moscow, Russia.
Bulletin of Experimental Biology and Medicine
|September 6, 2005
Abstract:
Circadian rhythms of DNA synthesis, mitotic activity, and duration of mitosis in rat liver were studied on postnatal days 3, 7, and 12. Some age-related peculiarities of these rhythms were revealed. Epidermal growth factor was found to play an important role in the formation of cell proliferation rhythm during the early postnatal ontogeny and in the regulation of the pool of proliferating hepatocytes.
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