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Related Experiment Videos

Transurethral laser prostatectomy in the canine model.

L B Kandel1, L H Harrison, D L McCullough

  • 1Department of Urology, State University of New York, Stony Brook 11794-8093.

Lasers in Surgery and Medicine
|January 1, 1992
PubMed
Summary

Transurethral laser prostatectomy using Neodymium:YAG laser is effective in dogs. Direct contact and higher power settings (70-100W) achieved significant tissue vaporization for prostatectomy.

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Area of Science:

  • Veterinary Surgery
  • Urology
  • Laser Technology

Background:

  • Transurethral prostatectomy is a common procedure for benign prostatic hyperplasia.
  • Laser technology offers potential for minimally invasive surgical interventions.
  • Evaluating novel laser techniques in animal models is crucial for clinical translation.

Purpose of the Study:

  • To devise and evaluate a transurethral prostatectomy technique using a Neodymium:YAG laser.
  • To assess the safety and efficacy of this laser prostatectomy method in a canine model.

Main Methods:

  • Six dogs underwent transurethral laser prostatectomy after perineal urethrostomy.
  • Neodymium:YAG laser was applied with fiberoptic light guide in direct contact with prostate tissue.
  • Power settings ranged from 70 to 100 watts.

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  • Efficacy was assessed via retrograde urethrography, ultrasonography, cystoscopy, and histology.

    • Main Results:

    • Non-contact laser application (40-70W) resulted in coagulation necrosis and minimal tissue removal.
    • Direct contact laser application (70-100W) achieved significant tissue vaporization and large prostatectomy defects.
    • The procedure was deemed safe and effective in the canine model.

    Conclusions:

    • Transurethral laser prostatectomy using Neodymium:YAG laser is a safe and effective technique.
    • Direct contact application and higher power settings (70-100W) are crucial for successful tissue vaporization.
    • This canine model demonstrates the potential of Neodymium:YAG laser prostatectomy for clinical use.