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Related Experiment Videos

Cat-scratch disease in elderly patients.

Ronen Ben-Ami1, Moshe Ephros, Boaz Avidor

  • 1Infectious Disease Unit, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel. rbenami1@zahav.net.il

Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America
|September 6, 2005
PubMed
Summary

Cat-scratch disease (CSD) presents differently in elderly individuals, often lacking typical symptoms like lymphadenopathy. Atypical CSD presentations, such as endocarditis, are more common in older adults, potentially delaying diagnosis.

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Area of Science:

  • Infectious Diseases
  • Bacteriology
  • Epidemiology

Background:

  • Cat-scratch disease (CSD) is typically seen in children and young adults.
  • CSD in elderly patients remains poorly characterized and may be underdiagnosed.

Purpose of the Study:

  • To characterize CSD in elderly patients.
  • To compare clinical and demographic features of CSD in elderly versus nonelderly individuals.

Main Methods:

  • Retrospective study of CSD cases diagnosed between 1991-2002.
  • Comparison of patients aged ≥60 years (elderly) with those aged <60 years (nonelderly).

Main Results:

  • Elderly patients (6% of 846) showed less lymphadenopathy but more general malaise.

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  • Atypical CSD, including endocarditis and encephalitis, was significantly more frequent in the elderly.
  • Diagnosis was delayed (>6 weeks) in nearly 30% of elderly patients.
  • Conclusions:

    • CSD clinical presentation differs significantly between elderly and nonelderly patients.
    • Atypical CSD, particularly endocarditis, is more prevalent in older adults.
    • Clinician awareness is crucial to avoid delayed diagnosis and unnecessary procedures in elderly CSD patients.