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Related Experiment Videos

Telephone-administered psychotherapy for depression.

David C Mohr1, Stacey L Hart, Laura Julian

  • 1Veterans Administration Medical Center, University of California, San Francisco 94121, USA. dmohr@itsa.ucsf.edu

Archives of General Psychiatry
|September 7, 2005
PubMed
Summary

Telephone-administered cognitive-behavioral therapy (T-CBT) significantly improved depression and positive affect in multiple sclerosis patients. The specific skills-training component of T-CBT offered benefits beyond general support, though these differences diminished over time.

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Area of Science:

  • Psychiatry
  • Clinical Psychology
  • Telehealth

Background:

  • Telephone-administered cognitive-behavioral therapy (T-CBT) is a proven treatment for depression.
  • However, the specific contribution of T-CBT's skills-training component versus nonspecific factors remains unclear.

Purpose of the Study:

  • To evaluate the efficacy of a 16-week T-CBT program.
  • To compare T-CBT against a control condition designed to account for attention and nonspecific therapy effects.

Main Methods:

  • A randomized controlled trial was conducted with 127 participants experiencing depression and functional impairments due to multiple sclerosis.
  • Participants received either 16 weeks of T-CBT or 16 weeks of telephone-administered supportive emotion-focused therapy.
  • Outcomes were assessed using the Hamilton Depression Rating Scale, Structured Clinical Interview for DSM-IV, Beck Depression Inventory, and the Positive Affect scale.

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Main Results:

  • Both treatments led to significant improvements in depression and positive affect (P<.01).
  • T-CBT showed significantly greater improvements in major depressive disorder frequency (P = .02), Hamilton Depression Rating Scale scores (P = .02), and Positive Affect scores (P = .008) compared to the control.
  • These treatment gains were maintained at 12-month follow-up, although the differences between groups were no longer statistically significant.

Conclusions:

  • Telephone-administered T-CBT effectively improved depression and positive affect in patients with multiple sclerosis.
  • The specific cognitive-behavioral components of T-CBT provided benefits beyond nonspecific therapeutic effects.
  • Low attrition rates (5.5%) suggest good patient adherence to telephone-delivered interventions.