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Published on: September 11, 2018
Descriptive epidemiology of infant ingestion calls to a regional poison control center
Teresa J Coco1, William D King, Ann P Slattery
1Department of Pediatrics, Division of Pediatric Emergency Medicine, Children's Health System, University of Alabama at Birmingham, Birmingham, AL 35233, USA. teoco@peds.uab.edu
Insights
Therapeutic misadventures are common in infants under 6 months due to dosing errors. Educating caregivers on accurate medication measurement and administration can help prevent these dangerous incidents.
Area of Science:
- Pediatric Safety
- Medication Errors
- Public Health
Background:
- Infants under 6 months are a vulnerable population.
- Medication administration errors pose significant risks to infants.
Purpose of the Study:
- To describe the epidemiology of ingestions and therapeutic misadventures in infants 6 months of age or younger.
- To identify common causes of medication errors in this age group.
Main Methods:
- Retrospective chart review of poison center cases.
- Analysis of 358 cases involving infants younger than 6 months.
Main Results:
- 53% of cases involved therapeutic misadventures.
- Caregiver dosing errors (incorrect measurement, dosing interval, route, repeated dosing) accounted for 41% of misadventures.
- Pharmacy errors and wrong medication administration occurred in 3% and 9% of cases, respectively.
Conclusions:
- Therapeutic misadventures due to dosing errors are prevalent in infants under 6 months.
- Inaccurate measurement, repeated dosing, incorrect intervals, and wrong routes are primary causes.
- Healthcare providers should educate caregivers on proper medication administration and use of measuring devices to enhance prevention.
Objective:
This study was designed to describe the epidemiology of ingestions in infants 6 months of age or younger.
Methods:
A retrospective chart review from a convenience sample of poison center cases in infants younger than 6 months of age from December 28, 2002, to December 28, 2003, was reviewed.
Results:
A total of 358 cases were reviewed. Incorrectly measured dose, repeated dosing by different caregivers, incorrect dosing interval, and incorrect route accounted for 41% [95% CI, (36%, 46%)] of caregiver dosing misadventures. Ten cases (3%) were due to pharmacy error, and the wrong medication was given in 32 (9%) cases. The total therapeutic misadventure proportion was 53%. Eight percent were 10-fold dosing errors. Thirty-nine (11%) infants were evaluated in an emergency department and 9 (3%) infants were admitted to a health care facility.
Conclusions:
Therapeutic misadventures caused by dosing errors in infants younger than 6 months of age were prevalent. Most errors occurred with inaccurate measurement of the medication, repeated dosing by caregivers, incorrect dosing interval, and incorrect route. Healthcare providers could increase prevention of therapeutic misadventures by educating caregivers on proper administration of medications and by demonstrating the use of appropriate measuring devices.
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