The prognostic value of a QRS score during exercise testing

Andreas P Michaelides1, Maria-Niki K Aigyprladou, George K Andrikopoulos

  • 1Exercise Laboratory, Department of Cardiology, A' Cardiology Clinic, Medical School of Athens University, Hippokration Hospital, Athens, Greece. aigyptiadou@yahoo.gr

Clinical Cardiology
|September 8, 2005
PubMed

Insights

An abnormal QRS score during treadmill exercise testing is a significant predictor of cardiac mortality in patients with coronary artery disease (CAD). This finding highlights the QRS score's clinical value in predicting outcomes for individuals with established CAD.

Area of Science:

  • Cardiology
  • Exercise Physiology
  • Diagnostic Imaging

Background:

  • QRS score values correlate with coronary artery narrowing and myocardial ischemia extent.
  • Radionuclide imaging techniques have previously shown this association.

Purpose of the Study:

  • To assess the prognostic capability of abnormal QRS scores from treadmill exercise tests.
  • To investigate the predictive value of QRS scores in patients with established coronary artery disease (CAD).

Main Methods:

  • 309 patients with documented CAD underwent treadmill exercise testing and coronary arteriography.
  • Patients were prospectively followed for up to 36 months.

Main Results:

  • Abnormal QRS scores (<= -4) were significantly and independently linked to cardiac mortality.
  • A relative risk of 11.7 (p=0.002) was observed for cardiac mortality with abnormal QRS scores.

Conclusions:

  • The QRS score holds clinical utility in predicting outcomes for patients with documented CAD.
  • Incorporating the QRS score into exercise testing can aid in managing ischemic heart disease.
Abstract

Related Concept Videos

Electrocardiogram01:29

Electrocardiogram

An electrocardiogram (ECG or EKG) is a critical diagnostic tool that records the electrical signals produced by the heart during each heartbeat. This recording is achieved through electrodes placed strategically on the arms, legs, and chest. The electrocardiograph amplifies these signals and produces 12 distinct tracings, offering a comprehensive understanding of the heart's electrical activity.
Three major waveforms are present in a typical ECG recording: the P wave, the QRS complex, and the T...
Exercise Stress Test01:26

Exercise Stress Test

Introduction
Exercise stress testing, commonly known as a treadmill test, is a noninvasive procedure used to evaluate cardiovascular function and diagnose heart conditions.
Definition
An exercise stress test measures the heart's response to exertion using a treadmill or stationary bicycle. Chest electrodes record the heart's electrical activity through an ECG, and blood pressure is monitored regularly.
Purposes
ECG Interpretation of Rhythms01:24

ECG Interpretation of Rhythms

An electrocardiogram (ECG)graphically represents the heart's electrical activity on ECG paper or a monitor.
Components of the Electrocardiogram
The primary components of a normal ECG waveform in Normal sinus rhythm(NSR) include the P wave, PR interval, QRS complex, ST segment, T wave, and occasionally a U wave.
ECG waveforms are divided by vertical and horizontal lines at standard intervals.
The horizontal axis measures time and rate, and the vertical axis measures amplitude or voltage. When...
Correlation between ECG and Cardiac Cycle01:25

Correlation between ECG and Cardiac Cycle

The electrical signals recorded on an electrocardiogram (ECG) occur before the mechanical processes of contraction and relaxation during the cardiac cycle.
A cardiac action potential originates in the SA node and spreads throughout the atria and the AV node in approximately 0.03 seconds. This results in the P wave in an ECG and triggers atrial contraction. The action potential is then briefly slowed at the AV node, allowing the atria to contract and fill the ventricles with blood before...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...
Electrocardiogram Fundamentals01:28

Electrocardiogram Fundamentals

Introduction
An electrocardiogram (ECG) is a diagnostic tool for identifying cardiac conditions such as arrhythmias, conduction abnormalities, and myocardial ischemia.
Definition
An electrocardiogram (ECG) visualizes the heart's electrical activity by tracing the electrical movement associated with each heartbeat on a graph or monitor. As the heart beats, an electrical wave passes through it, correlating with the cardiac cycle events.
Parts of an ECG
An ECG utilizes electrodes on the skin to...