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Updated: Aug 16, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
The chemical constituents of Ligularia pleurocaulis
Mian Zhang1, Chao-Feng Zhang, Zheng-Tao Wang
1Department of Pharmacognosy, China Pharmaceutical University, Nanjing 210038, China. mianzhang@hotmail.com
Aim:
To study the chemical constituents of the underground part of Ligularia pleurocaulis (Franch.) Hand-Mazz.
Methods:
The dried roots and rhizomes of L. pleurocaulis were extracted with methanol. Isolation and purification were performed by silica gel column chromatography and recrystallization etc. Structures of the pure compounds were established on basis of spectral analysis.
Results:
Twelve compounds were obtained from L. pleurocaulis, they were 6-angeloyloxy-furanoligularenone (1), 2-oxo-3-hydroxy-eremophila-1(10),3,7(11),8-tetraen-8,12-olide (2), tiglic acid (3), oleanolic acid (4), lupeol (5), beta-sitosterol (6), daucosterol (7), caffeic acid (8), emodin (9), 7-methoxy-coumarin (10), ferulic acid (11) and 4-hydroxy-2,5-dimethoxy-benzaldehyde (12).
Conclusion:
Compound 1 is a new eremophilane and compound 2 is a new natural compound. All above compounds were obtained for the first time from L. pleurocaulis.
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