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Published on: June 2, 2014
Hypertension in headache patients? A clinical study
U Pietrini1, M De Luca, G De Santis
1Headache Center, Department of Internal Medicine, University of Florence, Florence, Italy. u.pietrini@libero.it
Insights
Hypertension is common in headache patients, especially those with chronic tension-type headache or medication-overuse headache. This finding suggests hypertension should be screened for in headache patients.
Area of Science:
- Neurology
- Cardiovascular Medicine
Background:
- Headache disorders are prevalent globally.
- Hypertension is a significant cardiovascular risk factor.
- The relationship between hypertension and various headache types requires further investigation.
Purpose of the Study:
- To determine the prevalence of hypertension among patients presenting to a Headache Center.
- To compare hypertension rates across different headache diagnoses.
Main Methods:
- A cross-sectional study involving 1486 consecutive outpatients at a Headache Center.
- Blood pressure was measured for all participants.
Main Results:
- Overall hypertension prevalence was 28%, significantly higher than in the general population.
- Hypertension was most prevalent in medication-overuse headache (60.6%) and chronic tension-type headache (55.3%).
- Hypertension was less common in migraine without aura (23%) and migraine with aura (16.9%).
Conclusions:
- Hypertension is frequently observed in headache patients, particularly those with chronic tension-type headache and medication-overuse headache.
- Hypertension may contribute to headache exacerbation and has therapeutic implications.
- Active screening for hypertension in headache patients is recommended.
Objectives:
The aim of the present study was to assess the prevalence of hypertension in patients with headache, coming to the observation of an Headache Center.
Materials And Methods:
A total of 1486 consecutive outpatients were examined, and blood pressure was determined in all patients.
Results:
Migraine without aura (MO) was the most common diagnosis, followed by migraine associated with tension-type headache, migraine with aura (MA), episodic tension-type headache (ETTH), chronic tension-type headache (CTTH), cluster headache (CH), and medication-overuse headache (MOH). Hypertension was present in 28% of the patients, and it was particularly common in MOH (60.6%), CTTH (55.3%), CH (35%), ETTH (31.4%), less common in MO (23%) and MA (16.9%). In all headache groups, the prevalence of hypertension was higher than in the general population, within all age groups. After adjustment for age and gender, hypertension was found to be more common in tension-type, and especially in CTTH, than in migraine. These findings could be affected by 'Berkson's bias': and should not be extrapolated to the general population, but apply only to the subpopulation of patients who come to the observation of an Headache Center, and who may have more disabling symptoms.
Conclusion:
Hypertension could be one of the factors leading to exacerbation of the frequency and severity of attacks, both in migraine and tension-type headache. Hypertension has important therapeutic implications and should be actively sought in headache patients, and more thoroughly investigated, with ad-hoc surveys in the general population.
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