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Etiologies and outcomes of status epilepticus in children

Ali Akbar Asadi-Pooya1, Alie Poordast

  • 1Shiraz University of Medical Sciences, Shiraz, Iran. asadipoa@sums.ac.ir

Epilepsy & Behavior : E&B
|September 9, 2005
PubMed

Insights

Fever is the most common cause of pediatric status epilepticus (SE), a serious condition. While age and sex don't impact outcomes, the cause of SE significantly influences recovery, with febrile seizures faring better than symptomatic causes.

Area of Science:

  • Pediatric Neurology
  • Critical Care Medicine

Background:

  • Status epilepticus (SE) is a critical pediatric emergency associated with high mortality and morbidity.
  • Understanding the causes and outcomes of SE in children is crucial for improving patient management.

Purpose of the Study:

  • To investigate the etiology and outcomes of status epilepticus in pediatric patients.
  • To identify factors influencing SE outcomes in children.

Main Methods:

  • A retrospective cross-sectional study was conducted on 135 pediatric patients (1 month to 15 years) admitted with SE.
  • Data were collected from 1999 to 2004 at Nemazee Hospital, Shiraz, Iran.
  • Outcomes were assessed using the Glasgow Outcome Score (GOS).

Main Results:

  • Fever was the most frequent cause of SE across all pediatric age groups and sexes.
  • While 14 patients died, 81 were discharged in good health.
  • SE etiology significantly impacted outcomes (P=0.017), with prolonged febrile seizures showing the best outcomes and symptomatic SE the worst.

Conclusions:

  • Fever remains the leading cause of pediatric SE, even in children over three years old, highlighting the importance of managing febrile seizures.
  • Patient age and sex did not significantly affect SE outcomes.
  • The etiology of SE is a critical determinant of patient outcomes in children.
Abstract

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