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Published on: July 20, 2014
Benign cutaneous pseudoglandular schwannoma: a case report
April Deng1, John Petrali, David Jaffe
1Department of Dermatology, University of Maryland, Baltimore, Maryland 21201, USA. adeng@som.umaryland.edu
The American Journal of Dermatopathology
|September 9, 2005
Summary
This study describes a rare benign cutaneous pseudoglandular schwannoma, a skin neoplasm with gland-like structures. This finding highlights the diverse morphology of schwannoma, aiding in diagnosis.
Area of Science:
- Dermatopathology
- Surgical Pathology
- Oncology
Background:
- Schwannomas are common peripheral nerve tumors.
- Variant types, including glandular and pseudoglandular schwannomas, are rare.
- Pseudoglandular schwannomas exhibit gland-like structures lined by Schwann cells.
Observation:
- A case of benign cutaneous schwannoma with predominantly gland-like spaces is presented.
- These spaces contained mucinous material and were lined by Schwann cells.
- Immunohistochemistry and ultrastructural studies confirmed Schwann cell origin.
Findings:
- The tumor was well circumscribed and showed minimal cytologic atypia, indicating benignity.
- This represents an unusual variant of cutaneous schwannoma.
- The presence of mucin-containing pseudoglandular spaces is a key feature.
Implications:
- This case expands the known morphologic spectrum of schwannoma.
- Increased awareness of this variant can aid in accurate diagnosis.
- Understanding schwannoma diversity is crucial for effective patient management.
