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Effects of copper on A-type potassium currents in acutely dissociated rat hippocampal CA1 neurons

Zhi-Dian Niu1, Kuai Yu, Yan Gu

  • 1Department of Neurobiology and Biophysics, School of Life Science, University of Science and Technology of China, Anhui, PR China.

Neuroreport
|September 9, 2005
PubMed

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The Role of Ion Channels in Neuronal Computation01:19

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A postsynaptic neuron usually receives numerous impulses from several other presynaptic neurons. The axon hillock of the postsynaptic neuron integrates all these signals and determines the likelihood of firing an action potential.
Sometimes a single EPSP is strong enough to induce an action potential in the postsynaptic neuron. However, multiple presynaptic inputs must often create EPSPs around the same time for the postsynaptic neuron to be sufficiently depolarized to fire an action potential.