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Updated: Aug 16, 2026
Ileectomy-induced Bile Overaccumulation in Mouse Intestine
Published on: August 21, 2017
[Effect of ileocecum interposition graft as pylorus replacement on glycometabolism]
Ji-jian Zhang1, Guang-jin Guo, Deng-jin Jiang
1Department of Surgical Applied Anatomy and Operative Surgery, The Third Military Medical University, Chongqing 400038, China. zhangjijian2004@yahoo.com.cn
Objective:
To evaluate the application of ileocecum interposition (ii) graft as pylorus replacement in alimentary reconstruction.
Methods:
Twenty- one minipigs were randomly divided into three groups: sham operation group (control group), B - i group and ii group. The levels of blood glucose were measured by quick blood glucose testing of paper at 0, 30, 60, 90, and 120 minutes of oral glucose after 60 and 120 post- operative days to compare gastric emptying of liquid feeds.
Results:
Two months after operation,the peak of blood glucose was (7.8+/- 1.0)mmol/ L, (7.1+/- 0.8)mmol/ L, (4.1+/- 0.4)mmol/ L in B - i, ii group and control group respectively, there were significant differences between the two operation groups and control group (P< 0.01). Four months after operation, the peak of blood glucose was (6.9+/- 1.0) mmol/ L, (5.2+/- 0.8)mmol/ L, (4.2+/- 0.5)mmol/ L, respectively, there was no significant difference between ii group and control group (P > 0.05),but there were significant differences between both of the above two groups and B - i group (P< 0.01).
Conclusion:
The ileocecum interposition graft can offer specific advantages over current reconstruction procedures.
