[Assessment of fetal fibronectin concentration in identifying patients at risk for preterm delivery]
Agnieszka Pieta-Dolińska1, Bogumił Jaczewski, Piotr Woźniak
1Klinika Perinatologii, Instytutu Centrum Zdrowia Matki Polki, Lódź.
Design:
Identifying patients at risk for preterm delivery continues to be difficult.
Objectives:
This study aimed at evaluating fetal fibronectin concentrations in cervical secretions measured by an enzyme-linked immunosorbent assay, as a tool for of premature delivery screening in patients with preterm uterine contractions.
Materials And Methods:
Symptomatic 115 women, admitted to Department of Perinatology (RIPMMH) between 24 weeks 0 days and 34 weeks 6 days, with intact amniotic membranes, single pregnancy, cervical dilatation <3 cm and with no cerclage were included. Samples of the cervical secretion were taken every week until the delivery or to hospital discharge.
Results:
The enzyme-linked immunosorbent assays revealed sensitivity of 73.7% and specificity of 90.9%.
Conclusions:
This test was found to be a good tool for the prediction of premature delivery.
