Related Experiment Video
Updated: Aug 16, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
[Antibiotic administration in preterm delivery]
Agnieszka Pieta-Dolińska1, Bogumił Jaczewski, Jadwiga Wardecka
1Klinika Perinatologii, Instytutu Centrum Zdrowia Matki Polki, Lódź.
Design:
Although an association between subclinical intrauterine infection and preterm birth is well established, there is conflicting evidence regarding the benefits of antibiotic administration in women in preterm labor.
Objectives:
We attempted to determine the effect of antibioticotherapy in mothers on congenital neonatal infection.
Materials And Methods:
The study group consisted of 1049 pregnant women with imminent preterm labor hospitalized in Clinics of The Research Institute Polish Mother's Memorial Hospital.
Results:
244 women delivered preterm and no significant difference in neonatal outcomes could be detected in two groups with intact membranes and preterm premature rupture of membranes.
Conclusions:
The results of this study do not support the routine use of antibiotic administration in women with preterm labor.
Related Concept Videos
Microbiota Modulation by Antibiotics
Development of the Oral Microbiota
Urinary Tract Infection IV: Nursing Management
Drug Dosing: Infants and Children
Acute Pyelonephritis II: Diagnostic Studies and Management
Intrauterine Drug Delivery Systems