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Updated: Aug 16, 2026

Guide Wire Assisted Catheterization and Colored Dye Injection for Vascular Mapping of Monochorionic Twin Placentas
Published on: September 5, 2011
[Fetal warfarin syndrome in twin pregnancy]
Barbara Królak-Olejnik1, Antoni Pyrkosz, Jerzy Lagan
1Katedra i Klinika Perinatologii i Ginckologii w Zabrzu, SIAM, Katowicach. olejnik@pik-net.pl
Abstract:
We describe a pair of twins, whose mother was being treated by oral anticoagulant drugs, as a result of having received mitral heart valve implantation in the past. The male twins monochorionic, monoamniotic--but one infant showed the features of fetal warfarin syndrome. In the study we discussed the pharmacogentetics and individual variation in the human metabolism during treatment with warfarin-perinatal growth and prevalence of congenital malformations. We analysed the threats to the fetus and mother, connected with administration of anticoagulant drugs.
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