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Updated: Aug 12, 2026

Getting to Compliance in Forced Exercise in Rodents: A Critical Standard to Evaluate Exercise Impact in Aging-related Disorders and Disease
Published on: August 22, 2014
[Cellular functional changes in the endocrine system of the rats upon exposure to coal rock dust and during exercise]
Abstract:
Exposure to coal rock dust in combination with exercise for 2 months was found to have a negative impact on cellular metabolism in the endocrine system. The early form of anthracosilicosis developed in this period. Cytomorphological study revealed cellular changes in the pituitary, thyroid, parathyroid, and pancreatic glands. The cells of the endocrine organs are functionally tense upon exposure to toxic and physical factors and they are most vulnerable in this period of an experiment.
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