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Y-27632 Enriches the Yield of Human Melanocytes from Adult Skin Tissues
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Y-27632 Enriches the Yield of Human Melanocytes from Adult Skin Tissues

Published on: July 8, 2020

[Lipotropin (lipotropic hormone: LPH), melanocyte-stimulating hormone (MSH)]

Yuzuru Kato1

  • 1University Hospital, Shimane University School of Medicine.

Nihon Rinsho. Japanese Journal of Clinical Medicine
|September 10, 2005
PubMed
Abstract

No abstract available in PubMed .

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A hair follicle or HF is a small part of the skin that produces the hair shaft. Paul Gerson Unna was the first to observe a bulge in the human hair follicle's outer root sheath (ORS). The bulge is present between the sebaceous gland and the arrector pili muscle and is the niche for hair follicle stem cells (HFSCs). The bulge is also a niche for melanocyte stem cells, and their loss results in graying of hair. The HFSCs express Sox9 and Lhx2, which help them maintain stemness and prevent...

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