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Updated: Aug 16, 2026

Evaluating the Effectiveness of Cancer Drug Sensitization In Vitro and In Vivo
Published on: February 6, 2015
Evaluation of toxicities induced by chemotherapy in breast cancer patients
1Department of Biochemistry, University of Karachi, Karachi 75270, Pakistan.
Abstract:
The study includes the breast cancer female patients who had received chemotherapy (CMF, tamoxifen) and the newly diagnosed breast cancer patients, who had not received any chemotherapy. The patients who had received six cycles of CMF had shown low RBC, WBC and platelet count, elevated levels of SGPT, alkaline phosphatase and lactate dehydrogenase as compared to newly diagnosed breast cancer patients. The RBC count is increased in patients who had received CMF and tamoxifen as compared to the patients received only CMF, the alkaline phosphatase level is also declined in patients who had received CMF and tamoxifen as compared to the patients received CMF only.
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