Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A new numerical concept for modeling hydroxyapatite in human cortical bone.

J M Crolet1, M Racila, R Mahraoui

  • 1Laboratoire de Mathématiques, UMR 6623, Université de Franche, Comté, France. jmcrolet@univ-fcomte.fr

Computer Methods in Biomechanics and Biomedical Engineering
|September 13, 2005
PubMed
Summary

This study introduces a new model for human cortical bone, revealing that bone

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Surgical management of dysthyroid optic neuropathy: A systematic review.

Journal of stomatology, oral and maxillofacial surgery·2023
Same author

Comparison of pulsed-field gel electrophoresis and whole-genome-sequencing-based typing confirms the accuracy of pulsed-field gel electrophoresis for the investigation of local Pseudomonas aeruginosa outbreaks.

The Journal of hospital infection·2020
Same author

[Enhanced recovery after surgery in colorectal surgery].

Revue medicale de Liege·2020
Same author

Bilateral total deafness after preparation of wild boar meat.

European annals of otorhinolaryngology, head and neck diseases·2020
Same author

A sudden bilateral hearing loss caused by inner ear hemorrhage.

European annals of otorhinolaryngology, head and neck diseases·2019
Same author

First report of Beet virus Q in Belgium.

Plant disease·2019

Area of Science:

  • Biomaterials Science
  • Computational Mechanics
  • Orthopedic Research

Background:

  • Human cortical bone exhibits complex heterogeneity.
  • Understanding its physical properties is crucial for biomechanics and medical applications.
  • Existing models may not fully capture nanoscale interactions.

Purpose of the Study:

  • To develop a novel computational model for human cortical bone.
  • To investigate the influence of collagen and hydroxyapatite (Hap) at the nanoscale.
  • To determine the factors contributing to bone's anisotropic properties.

Main Methods:

  • Utilized homogenization theory for numerical simulations.
  • Defined a new entity, the elementary volume of mineral content (EVMC), at the nanoscopic scale.

Related Experiment Videos

  • Simulated various structural configurations of bone components.

    • Main Results:

    • The model accurately computes physical properties of heterogeneous cortical bone.
    • Identified the elementary volume of mineral content (EVMC) as a key nanoscopic entity.
    • Demonstrated that Hap crystal properties and organization significantly impact bone anisotropy.

    Conclusions:

    • Bone anisotropy arises not solely from haversian systems but also from hydroxyapatite (Hap) crystal characteristics.
    • The new EVMC model provides insights into nanoscale contributions to bone mechanics.
    • This approach allows for testing diverse structural configurations and predicting bone properties.