Resolution of a large left ventricular thrombus with anticoagulation alone
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Updated: Aug 16, 2026

Cardiac Magnetic Resonance for the Evaluation of Suspected Cardiac Thrombus: Conventional and Emerging Techniques
Published on: June 11, 2019
Syed-Mehdi H Zaidi1, Tarig S Al-Khuwaitir, Bashir A Wani
1Departments of Cardiology, Riyadh Medical Complex, Riyadh,Kingdom of Saudi Arabia.. Syedmehdi5@hotmail.com
Insights
Dilated cardiomyopathy can lead to dangerous heart thrombi. This case shows a large left ventricular thrombus successfully treated with anticoagulation alone, avoiding invasive procedures.
Area of Science:
- Cardiology
- Cardiac Surgery
- Internal Medicine
Background:
- Dilated cardiomyopathy is linked to left ventricular dysfunction, increasing the risk of intracardiac thrombus formation.
- Left ventricular thrombi pose an embolic risk, potentially leading to severe complications.
- Current management strategies for left ventricular thrombi remain a subject of debate.
Observation:
- A case involving an unusually large left ventricular thrombus was observed.
- The thrombus was associated with dilated cardiomyopathy and left ventricular dysfunction.
Findings:
- The large left ventricular thrombus demonstrated complete resolution following anticoagulation therapy.
- No invasive interventions were required for thrombus management.
Implications:
- Conservative management with anticoagulation may be a viable option for select cases of large left ventricular thrombi.
- This approach could potentially help patients avoid more invasive and risky procedures.
- Further research is warranted to establish definitive guidelines for managing left ventricular thrombi.
Abstract:
Dilated cardiomyopathy and the resultant left ventricular dysfunction are risk factors for thrombus formation in the heart, reflecting the intimate relationship between structure and function in this vital organ. Once formed, depending on size, location, and mobility, left ventricular thrombi have the tendency to embolize, sometimes with dire consequences. Proper management of these thrombi is still controversial. We present a case of an unusual large thrombus, which resolved with anticoagulation therapy alone, giving hope that more invasive intervention can safely be circumvented.
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