Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Developments in cardiovascular imaging.

T Marwick1

  • 1Department of Medicine, PA Hospital, University of Queensland, Brisbane 4012, Australia. tmarwick@medicine.pa.uq.edu.au

Idrugs : the Investigational Drugs Journal
|September 13, 2005
PubMed
Summary

Cardiac imaging techniques offer a promising avenue for evaluating new cardiovascular drugs. These methods allow for shorter studies with fewer patients, providing valuable prognostic information for better treatment decisions.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Mechanical synchrony and survival in heart failure.

Heart (British Cardiac Society)·2010
Same author

Prognosis of patients with ischaemic cardiomyopathy after coronary revascularisation: relation to viability and improvement in left ventricular ejection fraction.

Heart (British Cardiac Society)·2009
Same author

Use of peak systolic strain as an index of regional left ventricular function: comparison with tissue Doppler velocity during dobutamine stress and myocardial ischemia.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography·2000
Same author

Cost analysis of diagnostic testing for coronary artery disease in women with stable chest pain. Economics of Noninvasive Diagnosis (END) Study Group.

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology·1999
Same author

Standardized guidelines for the interpretation of dobutamine echocardiography reduce interinstitutional variance in interpretation.

The American journal of cardiology·1999
Same author

Head-to-head comparison of exercise-redistribution-reinjection thallium single-photon emission computed tomography and low dose dobutamine echocardiography for prediction of reversibility of chronic left ventricular ischemic dysfunction.

Journal of the American College of Cardiology·1996

Area of Science:

  • Cardiology
  • Medical Imaging
  • Pharmacology

Background:

  • Cardiovascular drug development is advancing rapidly.
  • Traditional outcome studies can be lengthy and resource-intensive.
  • Physiological parameters measured by cardiac imaging show prognostic value.

Purpose of the Study:

  • To review cardiac imaging techniques for assessing cardiovascular therapies.
  • To highlight the use of physiological parameters as alternative study endpoints.
  • To discuss the prognostic power of imaging in clinical decision-making.

Main Methods:

  • Review of current and emerging cardiac imaging modalities.
  • Analysis of physiological parameters measured by these techniques.
  • Evaluation of prognostic value and efficiency for clinical trials.

Main Results:

  • Cardiac imaging enables the use of physiological processes as surrogate endpoints.
  • Imaging studies can be shorter and require fewer patients than traditional outcome studies.
  • Physiological assessments via imaging provide significant prognostic insights.

Conclusions:

  • Cardiac imaging techniques are valuable tools in cardiovascular drug development.
  • Utilizing imaging endpoints can expedite the evaluation of new therapies.
  • The prognostic power of imaging supports cost-effective, optimized clinical decision-making.

Related Experiment Videos