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Updated: Mar 4, 2026

Murine Bilateral Renal Lymphadenectomy
Published on: December 30, 2025
Primary renal lymphoma presenting with hypertension
Amy M Becker1, Daniel C Bowers, Linda R Margraf
1Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390-9063, USA.
Primary renal lymphoma (PRL) is rare, typically affecting adults. This case highlights an asymptomatic child with hypertension, presenting an unusual manifestation of this kidney cancer.
Area of Science:
- Oncology
- Pediatric Nephrology
Background:
- Primary renal lymphoma (PRL) is an exceptionally rare malignancy, infrequently diagnosed in pediatric populations.
- Typical PRL presentations involve hematuria, flank pain, abdominal mass, and significant weight loss, predominantly in adult patients.
Observation:
- This report details a pediatric case initially presenting with hypertension, without the classic PRL symptoms.
- The patient was asymptomatic, underscoring the diagnostic challenge posed by atypical presentations.
Findings:
- The child was diagnosed with primary renal lymphoma, an uncommon finding in this age group and clinical context.
- Hypertension was the sole presenting clinical sign leading to the diagnosis.
Implications:
- This case expands the spectrum of clinical manifestations for primary renal lymphoma in children.
- It emphasizes the importance of considering rare diagnoses, including PRL, in pediatric patients with unexplained hypertension.
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