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[Splenic marginal zone lymphoma. One case report].

Faouzi El Mezni1, Abdelhatteh Zeddini, Olfa Ismail

  • 1Service d'Anatomie Pathologique de l'Hôpital A Mami de L'Ariana, Tunisie.

La Tunisie Medicale
|September 15, 2005
PubMed
Summary

Splenic marginal zone lymphoma, a rare B cell cancer, can be indolent. This case shows a patient achieving normal blood counts two years post-splenectomy without further treatment.

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Area of Science:

  • Hematology
  • Oncology
  • Pathology

Background:

  • Splenic marginal zone lymphoma (SMZL) is a rare, indolent B-cell lymphoma.
  • It typically presents with splenomegaly and cytopenias.

Observation:

  • A 68-year-old woman presented with splenomegaly and pancytopenia.
  • Morphologic and immunophenotyping findings were consistent with SMZL.

Findings:

  • Diagnosis was confirmed pathologically via splenectomy specimen.
  • The patient experienced a complete hematologic recovery two years after surgery.

Implications:

  • This case highlights the potential for durable remission in SMZL following splenectomy.
  • It underscores the importance of pathological diagnosis in managing rare B-cell lymphomas.

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