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[Systemic lupus erythematosus and pregnancy]
Our study strengthens the view that successful pregnancy outcome can be achieved in most patients with SLE, although premature delivery and pregnancy-related complications are common. For the differential diagnosis of preeclampsia and lupus flare in pregnancy, levels of anti-DNA antibodies and complement C3 are valuable parameters. In patients with antibodies to phospholipids, no major clinical problems occurred provided that patients were treated with corticosteroids and low-dose aspirin. However, none of our patients with renal involvement of SLE had an uncomplicated pregnancy course.
Our study strengthens the view that successful pregnancy outcome can be achieved in most patients with SLE, although premature delivery and pregnancy-related complications are common. For the differential diagnosis of preeclampsia and lupus flare in pregnancy, levels of anti-DNA antibodies and complement C3 are valuable parameters. In patients with antibodies to phospholipids, no major clinical problems occurred provided that patients were treated with corticosteroids and low-dose aspirin. However, none of our patients with renal involvement of SLE had an uncomplicated pregnancy course.