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Related Experiment Videos

Normal pressure "herniation".

Robert W Pratt1, Stephan A Mayer

  • 1Department of Neurology, Columbia-Presbyterian Medical Center, New York, NY, USA.

Neurocritical Care
|September 15, 2005
PubMed
Summary
This summary is machine-generated.

Normal pressure hydrocephalus can cause delayed brainstem herniation after ventricular hemorrhage. Cerebrospinal fluid (CSF) siphoning can reverse this condition, offering a novel treatment approach.

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Area of Science:

  • Neurosurgery
  • Neurology

Background:

  • Normal pressure hydrocephalus (NPH) is a rare cause of brain herniation.
  • Delayed herniation following ventricular hemorrhage is exceptionally uncommon.

Observation:

  • A 52-year-old male presented with acute coma and extensor posturing post-ventricular hemorrhage.
  • External ventricular drain placement confirmed normal intracranial pressure despite ventriculomegaly.

Findings:

  • Negative-pressure cerebrospinal fluid (CSF) siphoning (50 mL) led to ventricular size reduction.
  • This intervention resulted in dramatic clinical recovery, reversing the comatose state.

Implications:

  • Normal pressure hydrocephalus can precipitate delayed brainstem herniation.
  • CSF siphoning presents a potential therapeutic strategy for reversing NPH-induced herniation.