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Paroxysmal sympathetic storm.

Alan L Diamond1, R Charlie Callison, Jahansouz Shokri

  • 1Department of Neurology, Saint Louis University School of Medicine, USA.

Neurocritical Care
|September 15, 2005
PubMed
Summary
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Paroxysmal sympathetic storm (PSS) is a rare condition causing severe autonomic dysfunction. Treatment with labetalol, morphine, and codeine effectively managed symptoms in two distinct patient cases.

Area of Science:

  • Neurology
  • Critical Care Medicine

Background:

  • Paroxysmal sympathetic storm (PSS) is a rare syndrome.
  • Characterized by episodic hypertension, hyperhidrosis, hyperthermia, tachycardia, tachypnea, and extensor posturing.

Observation:

  • This article details two cases of PSS.
  • One case followed traumatic brain injury.
  • The other case followed cardiac arrest.

Findings:

  • The first patient responded to a combination of labetalol, morphine, and codeine.
  • The second patient showed improvement with labetalol alone.

Implications:

  • These findings highlight the critical role of central opioid receptors.
  • Nonselective beta-adrenergic antagonists are important in managing catecholamine pathways.