Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Ischemic hepatitis: widening horizons.

N Gitlin1, K M Serio

  • 1University of California, San Francisco School of Medicine.

The American Journal of Gastroenterology
|July 1, 1992
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical trial: interferon alpha-2b continuous long-term therapy vs. repeated 24-week cycles for re-treating chronic hepatitis C.

Alimentary pharmacology & therapeutics·2007
Same author

Response to: Appropriate choice of proton pump inhibitor therapy in the prevention and management of NSAID-related gastrointestinal damage.

International journal of clinical practice·2006
Same author

Extended lamivudine retreatment for chronic hepatitis B: maintenance of viral suppression after discontinuation of therapy.

Hepatology (Baltimore, Md.)·1999
Same author

Liver function in postmenopausal women on estrogen-androgen hormone replacement therapy: a meta-analysis of eight clinical trials.

Menopause (New York, N.Y.)·1999
Same author

Acute hepatitis A: what's new with it?

The American journal of gastroenterology·1998
Same author

Role of hepatic iron index in the management of iron overload syndromes in 1990's.

The American journal of gastroenterology·1998
Same journal

Calendar of Courses, Symposiums and Conferences.

The American journal of gastroenterology·2026
Same journal

Molecular Nonendoscopic Tests for the Early Detection of Esophageal Squamous Carcinoma and High-Grade Dysplasia: Promising Progress.

The American journal of gastroenterology·2026
Same journal

ACG Clinical Guideline: Colonic Diverticulitis.

The American journal of gastroenterology·2026
Same journal

Continuing Medical Education Questions: July 2026.

The American journal of gastroenterology·2026
Same journal

Continuing Medical Education Questions: July 2026.

The American journal of gastroenterology·2026
Same journal

2026 CME Information.

The American journal of gastroenterology·2026
See all related articles

Ischemic hepatitis, a liver complication of severe hypotension, presents with rapid enzyme changes and reversible issues like kidney dysfunction and confusion. Early recognition is key for managing this condition.

Area of Science:

  • Hepatology
  • Critical Care Medicine
  • Nephrology

Background:

  • Ischemic hepatitis is a known complication of severe hypotension or cardiac failure.
  • Prognosis is typically linked to the underlying cause of hypotension, not the liver dysfunction itself.

Purpose of the Study:

  • To report previously undocumented clinical and biochemical abnormalities in ischemic hepatitis.
  • To identify key indicators for diagnosing ischemic hepatitis.

Main Methods:

  • Retrospective analysis of nine patients diagnosed with ischemic hepatitis.
  • Review of clinical and biochemical data until recovery or death.

Main Results:

  • All patients showed rapid, significant elevations in aspartate aminotransferase and lactic dehydrogenase, followed by quick normalization.

Related Experiment Videos

  • Six patients experienced abnormal serum glucose levels, with three requiring temporary insulin therapy.
  • All nine patients developed transient renal impairment and six had altered mental status, both resolving spontaneously.
  • Pre-existing anemia did not worsen hepatic ischemia manifestations.

    • Conclusions:

    • Ischemic hepatitis should be suspected in patients with recent systemic hypotension.
    • Key diagnostic indicators include a massive early rise in lactic dehydrogenase, rapid transaminase decline, and early mild/moderate renal failure.
    • Reversible renal failure, mental confusion, and hyperglycemia are common manifestations requiring prompt management.