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Related Experiment Videos

Aminophylline suppository-induced acute proctitis.

D Ueda1, H Azuma, Y Sakata

  • 1Department of Pediatrics, Asahikawa Medical College, Japan.

The American Journal of Gastroenterology
|July 1, 1992
PubMed
Summary

Aminophylline suppositories can cause acute hemorrhagic proctitis in children, a rare but serious side effect. This condition involves rectal bleeding and inflammation, requiring medical attention.

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Area of Science:

  • Pediatric Gastroenterology
  • Pharmacovigilance

Background:

  • Aminophylline suppositories are frequently prescribed for managing asthma in pediatric patients.
  • Rectal administration of medications can lead to localized adverse effects.

Observation:

  • A 9-year-old boy presented with anal hemorrhage following the use of an aminophylline suppository.
  • Proctosigmoidoscopy revealed rectal mucosal edema, hyperemia, and petechiae.

Findings:

  • A provocation test confirmed aminophylline suppository-induced acute hemorrhagic proctitis.
  • This diagnosis highlights a rare but significant adverse reaction to a common pediatric medication.

Implications:

  • Healthcare providers should be aware of this potential side effect when prescribing aminophylline suppositories.

Related Experiment Videos

  • Prompt recognition and diagnosis are crucial for appropriate management of acute hemorrhagic proctitis in children.