Related Experiment Video
Updated: Aug 16, 2026

Electromagnetic Source Imaging in Presurgical Evaluation of Children with Drug-Resistant Epilepsy
Published on: September 20, 2024
A 10-year-old girl with coexistent moyamoya disease and Graves' disease
Meredith R Golomb1, Jose Biller, Jodi L Smith
1Division of Pediatric Neurology, Department of Neurology, Indiana University School of Medicine, Riley Hospital, Indianapolis, Indiana, USA. mgolomb@iupui.edu
Abstract:
There are rare reports of young women with moyamoya disease associated with Graves' disease; we are unaware of any previous reports of this association in prepubescent girls. We report a 10-year-old girl who presented with multiple bilateral strokes. Cerebral angiography demonstrated moderate to severe stenosis of her bilateral distal internal carotid arteries and proximal anterior and middle cerebral arteries, which was greater on the right. Thyroid function tests demonstrated suppressed thyroid-stimulating hormone and elevated thyroid hormone levels. Serum antiphospholipid antibody screen demonstrated mild elevations of antiocardiolipin IgG. Possible mechanisms predisposing individuals to concurrent moyamoya and Graves' disease are discussed.
Related Concept Videos
Graves Disease II: Pathophysiology
Graves' Disease I: Introduction
Cushing Syndrome II: Pathophysiology
Hyperthyroidism II: Pathophysiology
Cushing Syndrome I: Introduction
Hyperthyroidism I: Introduction