Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hepatitis C, B, D, and A: contrasting features and liver function abnormalities in heroin addicts.

Journal of addictive diseases·2001
Same author

Intractable or chronic pain: there is a difference.

The Western journal of medicine·2000
Same author

PCR quantitation of fetal cells in maternal blood in normal and aneuploid pregnancies.

American journal of human genetics·1997
Same author

Cocaine abuse in methadone maintenance patients is associated with low serum methadone concentrations.

Journal of addictive diseases·1995
Same author

Seroprevalence of hepatitis A, B, C, and D markers and liver function abnormalities in intravenous heroin addicts.

Journal of addictive diseases·1995
Same author

Hepatitis C in intravenous drug addicts.

Archives of internal medicine·1994

Related Experiment Video

Updated: Jul 23, 2026

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
14:40

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings

Published on: October 25, 2015

Early amniocentesis: outcome, risks, and technical problems at less than or equal to 12.8 weeks.

F W Hanson1, F Tennant, S Hune

  • 1Department of Obstetrics and Gynecology, University of California, Davis.

American Journal of Obstetrics and Gynecology
|June 1, 1992
PubMed
Summary

Early genetic amniocentesis at 12 weeks gestation is a safe and viable option. This study found a low postprocedural loss rate, offering earlier prenatal genetic diagnostic information.

More Related Videos

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
09:03

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy

Published on: August 25, 2019

External Cephalic Version: Is it an Effective and Safe Procedure?
08:49

External Cephalic Version: Is it an Effective and Safe Procedure?

Published on: June 6, 2020

Related Experiment Videos

Last Updated: Jul 23, 2026

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings
14:40

Instrumentation of Near-term Fetal Sheep for Multivariate Chronic Non-anesthetized Recordings

Published on: October 25, 2015

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy
09:03

Semiconductor Sequencing for Preimplantation Genetic Testing for Aneuploidy

Published on: August 25, 2019

External Cephalic Version: Is it an Effective and Safe Procedure?
08:49

External Cephalic Version: Is it an Effective and Safe Procedure?

Published on: June 6, 2020

Area of Science:

  • Perinatal medicine
  • Prenatal diagnostics
  • Medical genetics

Background:

  • First-trimester genetic amniocentesis provides crucial prenatal diagnostic information.
  • Evaluating the safety and efficacy of amniocentesis performed at or before 12 weeks' gestation is important for early pregnancy management.

Purpose of the Study:

  • To assess the experience and outcomes of amniocentesis performed at less than or equal to 12 weeks' gestation.
  • To determine the safety and viability of early-onset genetic amniocentesis.

Main Methods:

  • Retrospective review of 936 patients undergoing genetic amniocentesis between 12 and 12.8 weeks' gestation.
  • Data collected included gestational age, indications for the procedure, needle insertion frequency, complications, and pregnancy outcomes.

Main Results:

  • The total postprocedural loss rate was 3.4% (7 miscarriages within 2 weeks, 21 before 28 weeks, 4 stillbirths/neonatal deaths).
  • 2.8% of fetuses were diagnosed with chromosomal abnormalities.
  • The spontaneous abortion rate in comparable non-amniocentesis pregnancies was estimated between 2.1% and 3.2%.

Conclusions:

  • Amniocentesis at 12 weeks' gestation is a feasible option for obtaining early prenatal genetic diagnostic information.
  • The procedure demonstrated a comparable safety profile to established methods, supporting its use in early pregnancy.