Transcriptome analysis of Pseudomonas aeruginosa growth: comparison of gene expression in planktonic cultures and developing and mature biofilms
Related Experiment Video
Updated: Aug 16, 2026

Assembly and Tracking of Microbial Community Development within a Microwell Array Platform
Published on: June 6, 2017
Richard D Waite1, Anastasia Papakonstantinopoulou, Eddie Littler
1MRC Molecular Pathogenesis Research Unit, Centre for Infectious Disease, Institute of Cell and Molecular Science, Barts and the London, Queen Mary School of Medicine and Dentistry, 4 Newark Street, London, E1 2AT, United Kingdom. R.D.Waite@qmul.ac.uk
Abstract:
The transcriptomes of logarithmic- and stationary-phase Pseudomonas aeruginosa planktonic cultures and static biofilms of different stages of development were compared. Developing and confluent biofilm transcriptomes were found to be related to those of logarithmic- and stationary-phase planktonic cultures, respectively. In addition, a number of novel genes were up-regulated in developing and confluent biofilms, including genes encoding putative solute transport proteins and transcriptional regulators, respectively.