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Updated: Aug 16, 2026

In Vivo Dynamics of Retinal Microglial Activation During Neurodegeneration: Confocal Ophthalmoscopic Imaging and Cell Morphometry in Mouse Glaucoma
Published on: May 11, 2015
Analyzing Sub-Classifications of Glaucoma via SOM Based Clustering of Optic Nerve Images
Sanjun Yan1, Syed Sibte Raza Abidi, Paul Habib Artes
1Health Informatics Lab, Faculty of Computer Science, Dalhousie University, Halifax, Canada.
Abstract:
We present a data mining framework to cluster optic nerve images obtained by Confocal Scanning Laser Tomography (CSLT) in normal subjects and patients with glaucoma. We use self-organizing maps and expectation maximization methods to partition the data into clusters that provide insights into potential sub-classification of glaucoma based on morphological features. We conclude that our approach provides a first step towards a better understanding of morphological features in optic nerve images obtained from glaucoma patients and healthy controls.
