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Pityriasis versicolor: Current concepts in Aetiology and Management
1Department of Medicine, University College Hospital, Ibadan.
The Nigerian Postgraduate Medical Journal
|September 15, 2005
Summary
Pityriasis versicolor, a chronic fungal infection, is caused by Malassezia species, with Malassezia globosa implicated. Management now includes systemic and topical antifungals, with prophylactic treatment recommended to prevent common relapses.
Area of Science:
- Dermatology
- Mycology
- Infectious Diseases
Background:
- Pityriasis versicolor is a common, chronic, relapsing skin condition.
- It is caused by Malassezia yeast, a normal skin commensal.
- Malassezia species classification has advanced with molecular techniques.
Purpose of the Study:
- To review current understanding of pityriasis versicolor.
- To discuss the etiology and contributing factors.
- To outline contemporary management strategies.
Main Methods:
- Literature review of pityriasis versicolor.
- Analysis of Malassezia species identification and classification.
- Evaluation of treatment modalities and relapse factors.
Main Results:
- Seven Malassezia species identified, with Malassezia globosa linked to pityriasis versicolor.
- Genetic predisposition and environmental factors (e.g., hyperhidrosis, immunosuppression) contribute to pathogenicity.
- Topical therapy historically led to high relapse rates.
Conclusions:
- Current management involves combined systemic and topical antifungals.
- Prophylactic treatment is crucial for preventing frequent relapses.
- Further research is needed to identify factors triggering Malassezia pathogenicity.
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