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Updated: Aug 16, 2026

Detection and Quantification of Mono-Rhamnolipids and Di-Rhamnolipids Produced by Pseudomonas aeruginosa
Published on: March 29, 2024
Production of rhamnolipids by Pseudomonas aeruginosa
Gloria Soberón-Chávez1, François Lépine, Eric Déziel
1Departamento de Bioprocesos y Biocatálisis, Instituto de Biotecnología, Universidad Nacional Autónoma de México, Mexico City, Mexico. gloria@biomedicas.unam.mx
Abstract:
Pseudomonas aeruginosa produces glycolipidic surface-active molecules (rhamnolipids) which have potential biotechnological applications. Rhamnolipids are produced by P. aeruginosa in a concerted manner with different virulence-associated traits. Here, we review the rhamnolipids biosynthetic pathway, showing that it has metabolic links with numerous bacterial products such as alginate, lipopolysaccharide, polyhydroxyalkanoates, and 4-hydroxy-2-alkylquinolines (HAQs). We also discuss the factors controlling the production of rhamnolipids and the proposed roles this biosurfactant plays in P. aeruginosa lifestyle.
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