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Rapid Detection of Fecal Antigen of Helicobacter pylori Infection Based on Double Antibody Sandwich Detection Technology
Published on: May 23, 2025
[Prevalence of H. pylori infection in the Polish child population]
Franciszek Iwańczak1, Barbara Iwańczak, Tomasz Pytrus
1II Katedra i Klinika Pediatrii, Gastroenterologii i Zywienia AM we Wrocławiu.
Insights
Social and economic factors significantly influence Helicobacter pylori infection rates in children. Prevalence varied by age, sex, and living environment, with higher rates in rural areas and older children.
Area of Science:
- Pediatrics
- Infectious Diseases
- Epidemiology
Background:
- Helicobacter pylori is a common human pathogen linked to upper gastrointestinal diseases.
- Infection is more prevalent in developing countries.
- Understanding pediatric H. pylori prevalence is crucial for public health.
Purpose of the Study:
- To determine the prevalence of H. pylori infection in children.
- To analyze infection rates based on age, sex, and geographic location (urban vs. rural).
- To investigate the association between socioeconomic status and H. pylori infection in pediatric populations.
Main Methods:
- A random sample of 1500 children was selected from urban and rural districts with varying socioeconomic indicators.
- Children were stratified into five age groups (under 1 to 16-18 years).
- A total of 478 children (31.89%) participated, with sex proportions considered.
Main Results:
- The overall H. pylori infection rate was 34.5%.
- Prevalence was lowest in Wroclaw (18.3%), higher in Oleśnica town (42.2%), and intermediate in Oleśnica rural district (38.8%).
- Higher infection rates were observed in older children (15-19 years) residing in rural areas. No correlation was found between infection and digestive symptoms.
Conclusions:
- Socioeconomic conditions demonstrably influence H. pylori infection frequency in children.
- Geographic location and age are significant factors in pediatric H. pylori prevalence.
- Further research may explore targeted interventions based on socioeconomic and geographic risk factors.
Unlabelled:
Helicobacter pylori is one of the most frequent pathogens of human. It plays a decisive role in the diseases of upper alimentary tract. Most infected subjects live in the developing countries. The aim of the study was to estimate the prevalence of H. pylori infection in children depending on age, sex and place of living.
Material And Methods:
For the purpose of epidemiological studies the District Center of Informatics and Regional Data Bank have randomly drawn 1500 children; 500 from each: City District of Wroclaw, Oleśnica district, and rural district of Oleśnica--the regions varying in the wealth of inhabitants, monthly wages and unemployment rate. The children were selected in five ranges of age: under 1 year of age, 2-5 years old, 6-10 years old, 11-15 years old, and 16-18 years old. The proportion of both sexes in each subpopulation was taken into consideration. Altogether 478 from the selected children (31.89%) participated in the study.
Results:
The average rate of H. pylori infection amounted to 34.5%. It was the lowest in Wroclaw--18.3%. In Oleśnica town district it was 42.2% and in Oleśnica rural district--38.8%. Higher rate of H. pylori infections was observed in youngsters aged 15 to 19 years living in rural area. No indication of the effects of H. pylori infections on the occurrence of symptoms from digestive system was observed.
Conclusions:
The studies have demonstrated an influence of social and economic conditions on the frequency of H. pylori infection in children.
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